Chemicals and Drugs

Thyroid Hormone Receptors

Specific high affinity binding proteins for THYROID HORMONES in target cells. They are usually found in the nucleus and regulate DNA transcription. These receptors are activated by hormones that leads to transcription, cell differentiation, and growth suppression. Thyroid hormone receptors are encoded by two genes (GENES, ERBA): erbA-alpha and erbA-beta for alpha and beta thyroid hormone receptors, respectively.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Specific high affinity binding proteins for THYROID HORMONES in target cells. They are usually found in the nucleus and regulate DNA transcription. These receptors are activated by hormones that leads to transcription, cell differentiation, and growth suppression. Thyroid hormone receptors are encoded by two genes (GENES, ERBA): erbA-alpha and erbA-beta for alpha and beta thyroid hormone receptors, respectively.

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Synonyms

22 entry terms
  • Receptors, Thyroid Hormone
  • Thyroid Hormone Receptor
  • DIT Receptors
  • Diiodotyrosine Receptor
  • Diiodotyrosine Receptors
  • MIT Receptors
  • Monoiodotyrosine Receptors
  • Receptors, DIT
  • Receptors, Diiodotyrosine
  • Receptors, MIT
  • Receptors, Monoiodotyrosine
  • Receptors, T3
  • Receptors, T4
  • Receptors, Thyroxine
  • Receptors, Triiodothyronine
  • T3 Receptor
  • T3 Receptors
  • T4 Receptor
  • T4 Receptors
  • Thyroxine Receptor
  • Thyroxine Receptors
  • Triiodothyronine Receptors

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Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

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Indexing Annotation

coordinate with specific thyroid hormone

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History Note

87; PROTO-ONCOGENE PROTEIN ERBA was (NM) 1987-93

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Previous Indexing

  • Receptors, Endogenous Substances (1973-1986)
  • Thyroid Hormones (1966-1986)
  • Thyroxine (1966-1986)
  • Triiodothyronine (1966-1986)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.624.664.700.830w
  2. D12.776w.826w.850w

MeSH Record

NLM Classification

WK 202

AMA Style

References

  1. National Library of Medicine. Thyroid Hormone Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D011988. http://id.nlm.nih.gov/mesh/2026/D011988
  2. Thyroid Hormone Receptors. In: Wikipedia. https://en.wikipedia.org/wiki/Thyroid_hormone_receptor
  3. Thyroid Hormone Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q2539644