Chemicals and Drugs

Thyroid Hormone Receptors beta

High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRB gene (also known as NR1A2, THRB1, or ERBA2 gene) as several isoforms produced by alternative splicing. Mutations in the THRB gene cause THYROID HORMONE RESISTANCE SYNDROME.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRB gene (also known as NR1A2, THRB1, or ERBA2 gene) as several isoforms produced by alternative splicing. Mutations in the THRB gene cause THYROID HORMONE RESISTANCE SYNDROME.

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Classification

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Synonyms

15 entry terms
  • ERBA2 Gene Products
  • NR1A2 Gene Products
  • Receptors beta, Thyroid Hormone
  • THRB Gene Products
  • TR beta
  • Thyroid Hormone Receptor beta
  • c-erbA beta
  • Gene Products, ERBA2
  • Gene Products, NR1A2
  • Gene Products, THRB
  • c erbA beta
  • Thyroid Hormone Receptor beta-1
  • Thyroid Hormone Receptor beta-2
  • Thyroid Hormone Receptor beta 1
  • Thyroid Hormone Receptor beta 2

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2003; use RECEPTORS, THYROID HORMONE 1994-2002

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AMA Style

References

  1. National Library of Medicine. Thyroid Hormone Receptors beta. Medical Subject Headings (MeSH). 2026. Unique ID D037042. http://id.nlm.nih.gov/mesh/2026/D037042
  2. Thyroid Hormone Receptors beta. In: Wikidata. https://www.wikidata.org/wiki/Q7799753