Phenomena and Processes

erbA Genes

Genes related to the erbA DNA sequence that was first isolated from the avian erythroblastosis virus (ERYTHROBLASTOSIS VIRUS, AVIAN), v-erbA. In cells, erbA genes encode thyroid hormone receptors (RECEPTORS, THYROID HORMONE). Two distinct c-erbA genes have been identified: erbA-alpha located at 17q21; and erbA-beta located at 3p24. Truncations at the N- and C-terminals of erbA result in products resembling v-erbA. Truncations affect hormone responsiveness but not DNA binding capacity.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Genes related to the erbA DNA sequence that was first isolated from the avian erythroblastosis virus (ERYTHROBLASTOSIS VIRUS, AVIAN), v-erbA. In cells, erbA genes encode thyroid hormone receptors (RECEPTORS, THYROID HORMONE). Two distinct c-erbA genes have been identified: erbA-alpha located at 17q21; and erbA-beta located at 3p24. Truncations at the N- and C-terminals of erbA result in products resembling v-erbA. Truncations affect hormone responsiveness but not DNA binding capacity.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

See Also

MeSH Record

Synonyms

54 entry terms
  • Genes, erbA
  • erbA Gene
  • Genes, THRA
  • Genes, THRB
  • Genes, TR alpha
  • Genes, TR beta
  • Genes, TR-alpha
  • Genes, TR-beta
  • Genes, erbA alpha
  • Genes, erbA beta
  • Genes, erbA-alpha
  • Genes, erbA-beta
  • c-erbA Genes
  • c-erbA Proto-Oncogenes
  • v-erbA Genes
  • v-erbA Oncogenes
  • Gene, THRA
  • Gene, THRB
  • THRA Gene
  • THRA Genes
  • THRB Gene
  • THRB Genes
  • TR alpha Gene
  • TR alpha Genes
  • TR beta Gene
  • TR beta Genes
  • TR-alpha Gene
  • TR-alpha Genes
  • TR-beta Gene
  • TR-beta Genes
  • alpha Gene, TR
  • alpha Gene, erbA
  • alpha Genes, TR
  • alpha Genes, erbA
  • beta Gene, TR
  • beta Gene, erbA
  • beta Genes, TR
  • beta Genes, erbA
  • c erbA Genes
  • c erbA Proto Oncogenes
  • c-erbA Gene
  • c-erbA Proto-Oncogene
  • erbA alpha Gene
  • erbA alpha Genes
  • erbA beta Gene
  • erbA beta Genes
  • erbA-alpha Gene
  • erbA-alpha Genes
  • erbA-beta Gene
  • erbA-beta Genes
  • v erbA Genes
  • v erbA Oncogenes
  • v-erbA Gene
  • v-erbA Oncogene

MeSH Record

Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

MeSH Record

Indexing Annotation

erbA stands for "ERythroBlastosis virus, Avian"; GENES, ERBB & its specifics are also available; in titles & translations spell as erbA

MeSH Record

History Note

95

MeSH Record

Previous Indexing

  • Oncogenes (1984-1994)
  • Proto-Oncogenes (1987-1994)

MeSH Hierarchy

Tree Number

  1. G05.360w.340w.024.340w.375.500w.791.290

AMA Style

References

  1. National Library of Medicine. erbA Genes. Medical Subject Headings (MeSH). 2026. Unique ID D018776. http://id.nlm.nih.gov/mesh/2026/D018776
  2. erbA Genes. In: Wikidata. https://www.wikidata.org/wiki/Q71236105