Phenomena and Processes

Post-Translational Protein Processing

Any of various enzymatically catalyzed post-translational modifications of PEPTIDES or PROTEINS in the cell of origin. These modifications include carboxylation; HYDROXYLATION; ACETYLATION; PHOSPHORYLATION; METHYLATION; GLYCOSYLATION; ubiquitination; oxidation; proteolysis; and crosslinking and result in changes in molecular weight and electrophoretic motility.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Any of various enzymatically catalyzed post-translational modifications of PEPTIDES or PROTEINS in the cell of origin. These modifications include carboxylation; HYDROXYLATION; ACETYLATION; PHOSPHORYLATION; METHYLATION; GLYCOSYLATION; ubiquitination; oxidation; proteolysis; and crosslinking and result in changes in molecular weight and electrophoretic motility.

MeSH Record

Classification

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MeSH Record

See Also

MeSH Record

Synonyms

31 entry terms
  • Amino Acid Modification, Post-Translational
  • Amino Acid Modification, Posttranslational
  • Post-Translational Amino Acid Modification
  • Post-Translational Modification
  • Post-Translational Modifications
  • Post-Translational Protein Modification
  • Posttranslational Amino Acid Modification
  • Posttranslational Modification
  • Posttranslational Modifications
  • Posttranslational Protein Processing
  • Protein Modification, Post-Translational
  • Protein Processing, Post Translational
  • Protein Processing, Post-Translational
  • Protein Processing, Posttranslational
  • Amino Acid Modification, Post Translational
  • Modification, Post-Translational
  • Modification, Post-Translational Protein
  • Modification, Posttranslational
  • Modifications, Post-Translational
  • Modifications, Post-Translational Protein
  • Modifications, Posttranslational
  • Post Translational Amino Acid Modification
  • Post Translational Modification
  • Post Translational Modifications
  • Post Translational Protein Modification
  • Post Translational Protein Processing
  • Post-Translational Protein Modifications
  • Processing, Post-Translational Protein
  • Processing, Posttranslational Protein
  • Protein Modification, Post Translational
  • Protein Modifications, Post-Translational

MeSH Record

Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

MeSH Record

Indexing Annotation

coord IM with specific protein /metab (IM) and with specific modification, for example, ACYLATION; AMINATION; DEAMINATION; PROTEIN ISOPRENYLATION; etc.; do not confuse with PROTEIN MODIFICATION, TRANSLATIONAL; DF: PROTEIN PROC POST

MeSH Record

History Note

83

MeSH Record

Previous Indexing

  • Translation, Genetic (1973-1982)

MeSH Hierarchy

Tree Numbers

  1. G02.111.660.871w.790.600w
  2. G02.111.691.600w
  3. G03w.734.871w.790.600w
  4. G05.308w.670.600w

MeSH Record

NLM Classification

QU 55

AMA Style

References

  1. National Library of Medicine. Post-Translational Protein Processing. Medical Subject Headings (MeSH). 2026. Unique ID D011499. http://id.nlm.nih.gov/mesh/2026/D011499
  2. Post-Translational Protein Processing. In: Wikipedia. https://en.wikipedia.org/wiki/Post-translational_modification
  3. Post-Translational Protein Processing. In: Wikidata. https://www.wikidata.org/wiki/Q898362