Phenomena and Processes

Protein Splicing

The excision of in-frame internal protein sequences (INTEINS) of a precursor protein, coupled with ligation of the flanking sequences (EXTEINS). Protein splicing is an autocatalytic reaction and results in the production of two proteins from a single primary translation product: the intein and the mature protein.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The excision of in-frame internal protein sequences (INTEINS) of a precursor protein, coupled with ligation of the flanking sequences (EXTEINS). Protein splicing is an autocatalytic reaction and results in the production of two proteins from a single primary translation product: the intein and the mature protein.

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Synonyms

3 entry terms
  • Protein Splicings
  • Splicing, Protein
  • Splicings, Protein

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Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

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History Note

97

MeSH Record

Previous Indexing

  • Protein Processing, Post-Translational (1990-1996)

MeSH Hierarchy

Tree Numbers

  1. G02.111.660.871w.790.600w.700w
  2. G02.111.691.600w.700w
  3. G03w.734.871w.790.600w.700w
  4. G05.308w.670.600w.700w

AMA Style

References

  1. National Library of Medicine. Protein Splicing. Medical Subject Headings (MeSH). 2026. Unique ID D019154. http://id.nlm.nih.gov/mesh/2026/D019154
  2. Protein Splicing. In: Wikipedia. https://en.wikipedia.org/wiki/Protein_splicing
  3. Protein Splicing. In: Wikidata. https://www.wikidata.org/wiki/Q899401