Phenomena and Processes

Protein Carbamylation

Non-enzymatic addition of carbamoyl (-CONH2) on protein or amino acid functional groups from isocyanic acid or CARBAMOYL-PHOSPHATE. Carbamylation may induce a structural change that results in a functional loss and serves as a biomarker for protein aging and disease pathophysiology.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Non-enzymatic addition of carbamoyl (-CONH2) on protein or amino acid functional groups from isocyanic acid or CARBAMOYL-PHOSPHATE. Carbamylation may induce a structural change that results in a functional loss and serves as a biomarker for protein aging and disease pathophysiology.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

9 entry terms
  • Protein Carbamoylation
  • Carbamoylation, Protein
  • Carbamylation, Protein
  • Protein Carbamoylations
  • Protein Carbamylations
  • Carbamoylation
  • Carbamylation
  • Carbamoylations
  • Carbamylations

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2019

MeSH Record

Previous Indexing

  • Carbamates (1966-2018)
  • Protein Processing, Post-Translational (2003-2018)

MeSH Hierarchy

Tree Numbers

  1. G02.111.660.871w.790.600w.250
  2. G02.111.691.600w.250
  3. G03w.673w.518
  4. G03w.734.871w.790.600w.250
  5. G05.308w.670.600w.250
  6. G07.775w.750w.625

AMA Style

References

  1. National Library of Medicine. Protein Carbamylation. Medical Subject Headings (MeSH). 2026. Unique ID D000077279. http://id.nlm.nih.gov/mesh/2026/D000077279
  2. Protein Carbamylation. In: Wikidata. https://www.wikidata.org/wiki/Q101817045