Structured Summary
Abstract
A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides.
MeSH Record
Classification
Related Concepts
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MeSH Record
Synonyms
5 entry terms
- Microsomal Monooxygenases
- Hydroxylases, Aryl Hydrocarbon
- Monooxygenases, Microsomal
- Xenobiotic Monooxygenases
- Monooxygenases, Xenobiotic
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
75
MeSH Record
Previous Indexing
- Hydroxylases (1971-1974)
- Polycyclic Hydrocarbons (1974)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Aryl Hydrocarbon Hydroxylases. Medical Subject Headings (MeSH). 2026. Unique ID D001189. http://id.nlm.nih.gov/mesh/2026/D001189
- Aryl Hydrocarbon Hydroxylases. In: Wikidata. https://www.wikidata.org/wiki/Q78145558