Structured Summary
Abstract
A liver microsomal cytochrome P450 hydroxylase that oxidizes a broad spectrum of substrates including STEROIDS, FATTY ACIDS, and XENOBIOTICS. Examples of pharmaceutical substrates for CYP2C8 include; PACLITAXOL; torsemide; and; AMODIAQUINE
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
12 entry terms
- CYP2C8
- CYPIIC8
- Cytochrome P450 MP-20
- Cytochrome P450, Family 2, Subfamily C, Polypeptide 8
- S-Mephenytoin 4-Hydroxylase
- 4-Hydroxylase, S-Mephenytoin
- CYP2C8, Cytochrome P-450
- Cytochrome P 450 CYP2C8
- Cytochrome P450 MP 20
- P-450 CYP2C8, Cytochrome
- P450 MP-20, Cytochrome
- S Mephenytoin 4 Hydroxylase
MeSH Record
Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2015
MeSH Record
Previous Indexing
- Aryl Hydrocarbon Hydroxylases (2002-2014)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Cytochrome P-450 CYP2C8. Medical Subject Headings (MeSH). 2026. Unique ID D065727. http://id.nlm.nih.gov/mesh/2026/D065727
- Cytochrome P-450 CYP2C8. In: Wikidata. https://www.wikidata.org/wiki/Q5014957