Structured Summary
Abstract
A cytochrome P450 aryl hydrocarbon hydroxylase that has specificity for ESTROGENS which it converts into 4-hydroxy estrogens. CYP1B1 has been shown to be physiologically important for FETAL DEVELOPMENT with mutations in the CYP1B1 gene resulting in congenital forms of GLAUCOMA and Peter's anomaly.
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Classification
Broader headings
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Synonyms
5 entry terms
- Cytochrome P450 CYP1B1
- Cytochrome P450, Family 1, Subfamily B, Polypeptide 1
- Cytochrome P4501B1
- Cytochrome P 450 CYP1B1
- P450 CYP1B1, Cytochrome
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
/antag: coordinate with CYTOCHROME P-450 ENZYME INHIBITORS
MeSH Record
History Note
2015
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AMA Style
References
- National Library of Medicine. Cytochrome P-450 CYP1B1. Medical Subject Headings (MeSH). 2026. Unique ID D065633. http://id.nlm.nih.gov/mesh/2026/D065633
- Cytochrome P-450 CYP1B1. In: Wikidata. https://www.wikidata.org/wiki/Q24772983