Phenomena and Processes

Inteins

The internal fragments of precursor proteins (INternal proTEINS) that are autocatalytically removed by PROTEIN SPLICING. The flanking fragments (EXTEINS) are ligated forming mature proteins. The nucleic acid sequences coding for inteins are considered to be MOBILE GENETIC ELEMENTS. Inteins are composed of self-splicing domains and an endonuclease domain which plays a role in the spread of the intein's genomic sequence. Mini-inteins are composed of the self-splicing domains only.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The internal fragments of precursor proteins (INternal proTEINS) that are autocatalytically removed by PROTEIN SPLICING. The flanking fragments (EXTEINS) are ligated forming mature proteins. The nucleic acid sequences coding for inteins are considered to be MOBILE GENETIC ELEMENTS. Inteins are composed of self-splicing domains and an endonuclease domain which plays a role in the spread of the intein's genomic sequence. Mini-inteins are composed of the self-splicing domains only.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

See Also

MeSH Record

Synonyms

11 entry terms
  • Intervening Protein Sequence
  • Introns, Protein
  • Protein Introns
  • Intein
  • Intervening Protein Sequences
  • Intron, Protein
  • Protein Intron
  • Protein Sequence, Intervening
  • Protein Sequences, Intervening
  • Sequence, Intervening Protein
  • Sequences, Intervening Protein

MeSH Record

Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2005

MeSH Record

Previous Indexing

  • Protein Splicing (1997-2004)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Inteins. Medical Subject Headings (MeSH). 2026. Unique ID D047668. http://id.nlm.nih.gov/mesh/2026/D047668
  2. Inteins. In: Wikipedia. https://en.wikipedia.org/wiki/Intein
  3. Inteins. In: Wikidata. https://www.wikidata.org/wiki/Q904261