Diseases

Congenital Adrenal Hyperplasia

A group of inherited disorders of the ADRENAL GLANDS, caused by enzyme defects in the synthesis of cortisol (HYDROCORTISONE) and/or ALDOSTERONE leading to accumulation of precursors for ANDROGENS. Depending on the hormone imbalance, congenital adrenal hyperplasia can be classified as salt-wasting, hypertensive, virilizing, or feminizing. Defects in STEROID 21-HYDROXYLASE; STEROID 11-BETA-HYDROXYLASE; STEROID 17-ALPHA-HYDROXYLASE; 3-beta-hydroxysteroid dehydrogenase (3-HYDROXYSTEROID DEHYDROGENASES); TESTOSTERONE 5-ALPHA-REDUCTASE; or steroidogenic acute regulatory protein; among others, underlie these disorders.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A group of inherited disorders of the ADRENAL GLANDS, caused by enzyme defects in the synthesis of cortisol (HYDROCORTISONE) and/or ALDOSTERONE leading to accumulation of precursors for ANDROGENS. Depending on the hormone imbalance, congenital adrenal hyperplasia can be classified as salt-wasting, hypertensive, virilizing, or feminizing. Defects in STEROID 21-HYDROXYLASE; STEROID 11-BETA-HYDROXYLASE; STEROID 17-ALPHA-HYDROXYLASE; 3-beta-hydroxysteroid dehydrogenase (3-HYDROXYSTEROID DEHYDROGENASES); TESTOSTERONE 5-ALPHA-REDUCTASE; or steroidogenic acute regulatory protein; among others, underlie these disorders.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

See Also

MeSH Record

Synonyms

5 entry terms
  • Adrenal Hyperplasia, Congenital
  • Hyperplasia, Congenital Adrenal
  • Adrenal Hyperplasias, Congenital
  • Congenital Adrenal Hyperplasias
  • Hyperplasias, Congenital Adrenal

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

80; was ADRENOGENITAL SYNDROME 1963-79

MeSH Hierarchy

Tree Numbers

  1. C12.050.351.875w.253w.090.500w
  2. C12.200.706w.316w.090.500w
  3. C12.800w.316w.090.500w
  4. C16w.131w.939w.316w.129.500w
  5. C16w.320w.033w
  6. C16w.320w.565w.925w.249w
  7. C18.452w.648w.925w.249w
  8. C19w.053w.440w
  9. C19w.391.119w.090.500w

MeSH Record

NLM Classification

WK 700

AMA Style

References

  1. National Library of Medicine. Congenital Adrenal Hyperplasia. Medical Subject Headings (MeSH). 2026. Unique ID D000312. http://id.nlm.nih.gov/mesh/2026/D000312
  2. Congenital Adrenal Hyperplasia. In: Wikipedia. https://en.wikipedia.org/wiki/Congenital_adrenal_hyperplasia
  3. Congenital Adrenal Hyperplasia. In: Wikidata. https://www.wikidata.org/wiki/Q366868