Structured Summary
Abstract
A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11B1 gene, is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
See Also
MeSH Record
Synonyms
14 entry terms
- 11 beta-Hydroxylase
- CYP 11B1
- CYP11B1
- Cytochrome P-450 CYP11B1
- Cytochrome P-450(11 beta)
- Cytochrome P450 11B1
- Steroid 11 Hydroxylase
- Steroid 11-Hydroxylase
- Steroid 11-beta-Monooxygenase
- Steroid-11-Hydroxylase
- 11 beta Hydroxylase
- Cytochrome P 450 CYP11B1
- Steroid 11 beta Hydroxylase
- Steroid 11 beta Monooxygenase
MeSH Record
Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2003 (1978)
MeSH Record
Previous Indexing
- Steroid Hydroxylases (1973-1977)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Steroid 11-beta-Hydroxylase. Medical Subject Headings (MeSH). 2026. Unique ID D013252. http://id.nlm.nih.gov/mesh/2026/D013252
- Steroid 11-beta-Hydroxylase. In: Wikipedia. https://en.wikipedia.org/wiki/Steroid_11%CE%B2-hydroxylase
- Steroid 11-beta-Hydroxylase. In: Wikidata. https://www.wikidata.org/wiki/Q904925