Chemicals and Drugs

Calcium Channels

Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue.

MeSH Record

Classification

Broader headings

Narrower headings

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MeSH Record

See Also

MeSH Record

Synonyms

20 entry terms
  • Calcium Channel
  • Calcium Channel Antagonist Receptor
  • Calcium Channel Antagonist Receptors
  • Calcium Channel Blocker Receptor
  • Calcium Channel Blocker Receptors
  • Ion Channel, Calcium
  • Ion Channels, Calcium
  • Receptors, Calcium Channel Antagonist
  • Receptors, Calcium Channel Blocker
  • VDCC
  • Voltage-Dependent Calcium Channel
  • Voltage-Dependent Calcium Channels
  • Calcium Channel, Voltage-Dependent
  • Calcium Channels, Voltage-Dependent
  • Calcium Ion Channel
  • Calcium Ion Channels
  • Channel, Voltage-Dependent Calcium
  • Channels, Voltage-Dependent Calcium
  • Voltage Dependent Calcium Channel
  • Voltage Dependent Calcium Channels

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

L-, N-, P-, Q-, R-, and T-Type CALCIUM CHANNELS are available

MeSH Record

History Note

89; RECEPTORS, CALCIUM CHANNEL BLOCKER was heading 1993 (was CALCIUM CHANNEL BLOCKER RECEPTOR (NM) 1983-92); CALCIUM CHANNEL ANTAGONIST RECEPTORS, CALCIUM CHANNEL BLOCKER RECEPTORS & RECEPTORS, CALCIUM CHANNEL ANTAGONIST were see RECEPTORS, CALCIUM CHANNEL BLOCKER 1993

MeSH Record

Previous Indexing

  • Calcium (1979-1988)
  • Ion Channels (1979-1988)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.530w.400w.150w
  2. D12.776w.543w.550w.450w.150w
  3. D12.776w.543w.585w.400w.150w

AMA Style

References

  1. National Library of Medicine. Calcium Channels. Medical Subject Headings (MeSH). 2026. Unique ID D015220. http://id.nlm.nih.gov/mesh/2026/D015220
  2. Calcium Channels. In: Wikipedia. https://en.wikipedia.org/wiki/Calcium_channel
  3. Calcium Channels. In: Wikidata. https://www.wikidata.org/wiki/Q15322916