Chemicals and Drugs

Calcium Release Activated Calcium Channels

Specialized calcium channels that localize to the ENDOPLAMSIC RETICULUM and PLASMA MEMBRANE. They contain the pore subunit ORAI1 PROTEIN which is activated by STROMAL INTERACTION MOLECULES upon intracellular calcium depletion.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Specialized calcium channels that localize to the ENDOPLAMSIC RETICULUM and PLASMA MEMBRANE. They contain the pore subunit ORAI1 PROTEIN which is activated by STROMAL INTERACTION MOLECULES upon intracellular calcium depletion.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

7 entry terms
  • CRAC Channel
  • CRAC Channels
  • Calcium Release Activated Calcium Channel
  • Calcium Release-Activated Calcium Channels
  • Calcium Release-Activated Channels
  • Calcium Release Activated Channels
  • Channel, CRAC

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017

MeSH Record

Previous Indexing

  • Calcium Channels (1995-2016)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Calcium Release Activated Calcium Channels. Medical Subject Headings (MeSH). 2026. Unique ID D000071739. http://id.nlm.nih.gov/mesh/2026/D000071739
  2. Calcium Release Activated Calcium Channels. In: Wikipedia. https://en.wikipedia.org/wiki/Calcium_release_activated_channel
  3. Calcium Release Activated Calcium Channels. In: Wikidata. https://www.wikidata.org/wiki/Q1283774