Chemicals and Drugs

Inositol 1,4,5-Trisphosphate Receptors

Intracellular receptors that bind to INOSITOL 1,4,5-TRISPHOSPHATE and play an important role in its intracellular signaling. Inositol 1,4,5-trisphosphate receptors are calcium channels that release CALCIUM in response to increased levels of inositol 1,4,5-trisphosphate in the CYTOPLASM.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Intracellular receptors that bind to INOSITOL 1,4,5-TRISPHOSPHATE and play an important role in its intracellular signaling. Inositol 1,4,5-trisphosphate receptors are calcium channels that release CALCIUM in response to increased levels of inositol 1,4,5-trisphosphate in the CYTOPLASM.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

22 entry terms
  • 1,4,5-INTP Receptor
  • INSP3 Receptor
  • IP3 Receptor
  • Inositol 1,4,5-Triphosphate Receptor
  • Inositol 1,4,5-Triphosphate Receptors
  • Inositol 1,4,5-Trisphosphate Receptor
  • Inositol Triphosphate Receptor
  • Inositol-1,4,5-Triphosphate Receptor
  • Receptor, Inositol-1,4,5-triphosphate
  • Receptor, INSP3
  • Receptor, IP3
  • Receptor, Inositol Triphosphate
  • Triphosphate Receptor, Inositol
  • INSP3 Receptor Type 1
  • INSP3 Receptor Type 2
  • INSP3 Receptor Type 3
  • Inositol 1,4,5-trisphosphate Receptor Subtype 3
  • Inositol 1,4,5-trisphosphate Receptor Type 1
  • Inositol 1,4,5-trisphosphate Receptor Type 2
  • Inositol 1,4,5-trisphosphate Receptor Type 3
  • Type 1 Inositol 1,4,5-trisphosphate Receptor
  • Type 3 Inositol 1,4,5-trisphosphate Receptor

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007(1986)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.530w.400w.150w.760w
  2. D12.776w.543w.550w.450w.150w.760w
  3. D12.776w.543w.585w.400w.150w.760w
  4. D12.776w.826w.179w

AMA Style

References

  1. National Library of Medicine. Inositol 1,4,5-Trisphosphate Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D053496. http://id.nlm.nih.gov/mesh/2026/D053496
  2. Inositol 1,4,5-Trisphosphate Receptors. In: Wikipedia. https://en.wikipedia.org/wiki/Inositol_trisphosphate_receptor
  3. Inositol 1,4,5-Trisphosphate Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q418917