Chemicals and Drugs

CD28 Antigens

Costimulatory T-LYMPHOCYTE receptors that have specificity for CD80 ANTIGEN and CD86 ANTIGEN. Activation of this receptor results in increased T-cell proliferation, cytokine production and promotion of T-cell survival.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Costimulatory T-LYMPHOCYTE receptors that have specificity for CD80 ANTIGEN and CD86 ANTIGEN. Activation of this receptor results in increased T-cell proliferation, cytokine production and promotion of T-cell survival.

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Classification

Broader headings

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See Also

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Synonyms

7 entry terms
  • Antigens, CD28
  • CD28 Antigen
  • T-Cell-Specific Surface Glycoprotein CD28
  • TP44 Receptor
  • Antigen, CD28
  • Receptor, TP44
  • T Cell Specific Surface Glycoprotein CD28

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2018 (1986)

MeSH Record

Previous Indexing

  • Antigens, CD (1990-1993)
  • Antigens, Differentiation, T-Lymphocyte (1986-1993)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.543w.750w.705w.222.500w
  2. D23.050w.301.264.894.128w
  3. D23.101w.100.894.128w

AMA Style

References

  1. National Library of Medicine. CD28 Antigens. Medical Subject Headings (MeSH). 2026. Unique ID D018106. http://id.nlm.nih.gov/mesh/2026/D018106
  2. CD28 Antigens. In: Wikipedia. https://en.wikipedia.org/wiki/CD28_family_receptor
  3. CD28 Antigens. In: Wikidata. https://www.wikidata.org/wiki/Q24774566