Chemicals and Drugs

Differentiation Antigens

Antigens expressed primarily on the membranes of living cells during sequential stages of maturation and differentiation. As immunologic markers they have high organ and tissue specificity and are useful as probes in studies of normal cell development as well as neoplastic transformation.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Antigens expressed primarily on the membranes of living cells during sequential stages of maturation and differentiation. As immunologic markers they have high organ and tissue specificity and are useful as probes in studies of normal cell development as well as neoplastic transformation.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

16 entry terms
  • Antigens, Differentiation
  • Differentiation Antigen
  • Differentiation Marker
  • Differentiation Markers
  • Marker Antigen
  • Marker Antigens
  • Markers, Differentiation
  • Antigen, Differentiation
  • Antigen, Marker
  • Antigens, Marker
  • Marker, Differentiation
  • Differentiation Antigens, Hairy Cell Leukemia
  • Leu Antigen
  • Leu Antigens
  • Antigen, Leu
  • Antigens, Leu

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

general or unspecified; prefer specific groups and specific differentiation antigens; note entry term LEU ANTIGENS but several specific Leu antigens are also available

MeSH Record

History Note

88; DIFFERENTIATION ANTIGENS, HAIRY CELL LEUKEMIA was see ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE 1988-91; LEU ANTIGENS was see ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1988

MeSH Record

Previous Indexing

  • Antigens (1966-1977)
  • Antigens, Neoplasm (1973-1987)
  • Antigens, Surface (1979-1987)
  • Cell Differentiation (1966-1987)
  • Cell Transformation, Neoplastic (1970-1987)
  • specific cell or tissue (1966-1987)

MeSH Hierarchy

Tree Numbers

  1. D23.050w.301.264
  2. D23.101w.100

MeSH Record

NLM Classification

QW 573

AMA Style

References

  1. National Library of Medicine. Differentiation Antigens. Medical Subject Headings (MeSH). 2026. Unique ID D000943. http://id.nlm.nih.gov/mesh/2026/D000943
  2. Differentiation Antigens. In: Wikidata. https://www.wikidata.org/wiki/Q66660278