Chemicals and Drugs

src-Family Kinases

A PROTEIN-TYROSINE KINASE family that was originally identified by homology to the Rous sarcoma virus ONCOGENE PROTEIN PP60(V-SRC). They interact with a variety of cell-surface receptors and participate in intracellular signal transduction pathways. Oncogenic forms of src-family kinases can occur through altered regulation or expression of the endogenous protein and by virally encoded src (v-src) genes.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A PROTEIN-TYROSINE KINASE family that was originally identified by homology to the Rous sarcoma virus ONCOGENE PROTEIN PP60(V-SRC). They interact with a variety of cell-surface receptors and participate in intracellular signal transduction pathways. Oncogenic forms of src-family kinases can occur through altered regulation or expression of the endogenous protein and by virally encoded src (v-src) genes.

MeSH Record

Classification

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MeSH Record

See Also

MeSH Record

Synonyms

24 entry terms
  • Protein-Tyrosine Kinases, src
  • Src Family Tyrosine Kinase
  • src Kinase
  • src Kinases
  • src Tyrosine Kinase
  • src Tyrosine Kinases
  • src-Family Kinase
  • src-Family Tyrosine Kinase
  • src-Family Tyrosine Kinases
  • Kinase, src
  • Kinase, src Tyrosine
  • Kinase, src-Family
  • Kinase, src-Family Tyrosine
  • Kinases, src
  • Kinases, src Protein-Tyrosine
  • Kinases, src Tyrosine
  • Tyrosine Kinase, src
  • Tyrosine Kinase, src-Family
  • Tyrosine Kinases, src
  • Tyrosine Kinases, src-Family
  • src Family Kinase
  • src Family Kinases
  • src Family Tyrosine Kinases
  • src Protein-Tyrosine Kinases

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

96

MeSH Record

Previous Indexing

  • Protein-Tyrosine Kinase (1986-1995)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.913w.696w.620.682w.725w.800w
  2. D12.776w.476.568w.800w

AMA Style

References

  1. National Library of Medicine. src-Family Kinases. Medical Subject Headings (MeSH). 2026. Unique ID D019061. http://id.nlm.nih.gov/mesh/2026/D019061
  2. src-Family Kinases. In: Wikipedia. https://en.wikipedia.org/wiki/Src_family_kinase
  3. src-Family Kinases. In: Wikidata. https://www.wikidata.org/wiki/Q7582406