Chemicals and Drugs

Proto-Oncogene Proteins pp60(c-src)

Membrane-associated tyrosine-specific kinases encoded by the c-src genes. They have an important role in cellular growth control. Truncation of carboxy-terminal residues in pp60(c-src) leads to PP60(V-SRC) which has the ability to transform cells. This kinase pp60 c-src should not be confused with csk, also known as c-src kinase.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Membrane-associated tyrosine-specific kinases encoded by the c-src genes. They have an important role in cellular growth control. Truncation of carboxy-terminal residues in pp60(c-src) leads to PP60(V-SRC) which has the ability to transform cells. This kinase pp60 c-src should not be confused with csk, also known as c-src kinase.

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Classification

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MeSH Record

Synonyms

18 entry terms
  • Phosphoprotein pp60(c-src)
  • Proto-Oncogene Protein pp60(c-src)
  • Proto-Oncogene Protein src
  • c-src Protein pp60
  • pp60 c-src
  • pp60(c-src)
  • src Proto-Oncogene Product
  • src Proto-Oncogene Protein pp60
  • Protein pp60, c-src
  • Protein src, Proto-Oncogene
  • Proto Oncogene Protein src
  • Proto-Oncogene Product, src
  • c src Protein pp60
  • c-src, pp60
  • pp60 c src
  • pp60, c-src Protein
  • src Proto Oncogene Product
  • src Proto Oncogene Protein pp60

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1991)

MeSH Record

Previous Indexing

  • Phosphoproteins (1983-1985)
  • Proto-Oncogene Proteins (1986-1990)

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AMA Style

References

  1. National Library of Medicine. Proto-Oncogene Proteins pp60(c-src). Medical Subject Headings (MeSH). 2026. Unique ID D016392. http://id.nlm.nih.gov/mesh/2026/D016392
  2. Proto-Oncogene Proteins pp60(c-src). In: Wikipedia. https://en.wikipedia.org/wiki/Proto-oncogene_tyrosine-protein_kinase_Src
  3. Proto-Oncogene Proteins pp60(c-src). In: Wikidata. https://www.wikidata.org/wiki/Q21109354