Structured Summary
Abstract
A process of GENETIC TRANSLATION whereby the formation of a peptide chain is started. It includes assembly of the RIBOSOME components, the MESSENGER RNA coding for the polypeptide to be made, INITIATOR TRNA, and PEPTIDE INITIATION FACTORS; and placement of the first amino acid in the peptide chain. The details and components of this process are unique for prokaryotic protein biosynthesis and eukaryotic protein biosynthesis.
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Synonyms
15 entry terms
- Chain Initiation, Peptide, Translational
- Peptide Chain Initiation, Translational
- Protein Biosynthesis Initiation
- Protein Chain Initiation, Translational
- Protein Translation Initiation
- Translation Initiation, Genetic
- Translation Initiation, Protein
- Translational Initiation, Protein
- Biosynthesis Initiation, Protein
- Genetic Translation Initiation
- Initiation, Genetic Translation
- Initiation, Protein Biosynthesis
- Initiation, Protein Translation
- Initiation, Protein Translational
- Protein Translational Initiation
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Aspects Covered
6 allowable subheadings
Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.
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Indexing Annotation
coordinate with specific peptide; for protein biosynthesis on the ribosome only; for non-ribosomal biosynthesis use PEPTIDE BIOSYNTHESIS, NUCLEIC ACID-INDEPENDENT
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History Note
73(71)
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Previous Indexing
- Peptides/biosynthesis (1966-1970)
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AMA Style
References
- National Library of Medicine. Translational Peptide Chain Initiation. Medical Subject Headings (MeSH). 2026. Unique ID D010442. http://id.nlm.nih.gov/mesh/2026/D010442
- Translational Peptide Chain Initiation. In: Wikidata. https://www.wikidata.org/wiki/Q71131453