Structured Summary
Abstract
A pharmaceutical preparation of emtricitabine and tenofovir that is used as an ANTI-HIV AGENT in the treatment and prevention of HIV INFECTIONS.
Chemical Identity
Chemical Information
- Molecular Formula
- C31H44FN8O17PS
- Molecular Weight
- 882.8 g/mol
- CAS Registry No.
- 731772-45-5
- IUPAC Name
- 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one;[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(propan-2-yloxycarbonyloxymethoxy)phosphoryl]oxymethyl propan-2-yl carbonate;(E)-but-2-enedioic acid
- InChIKey
- VERWQPYQDXWOGT-LVJNJWHOSA-N
- SMILES
- C[C@H](CN1C=NC2=C(N=CN=C21)N)OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C.C1[C@H](O[C@H](S1)CO)N2C=C(C(=NC2=O)N)F.C(=C/C(=O)O)\C(=O)O
- MeSH Unique ID
- D000069480
- Source
- PubChem CID 11954236
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
4 entry terms
- Emtricitabine Tenofovir Disoproxil Fumarate Drug Combination
- Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination
- Emtricitabine-Tenofovir Disoproxil Fumarate Drug Combination
- Truvada
MeSH Record
Aspects Covered
24 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2016 (2005)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Tenofovir Disoproxil Fumarate Drug Combination Emtricitabine. Medical Subject Headings (MeSH). 2026. Unique ID D000069480. http://id.nlm.nih.gov/mesh/2026/D000069480
- Tenofovir Disoproxil Fumarate Drug Combination Emtricitabine. In: Wikipedia. https://en.wikipedia.org/wiki/Emtricitabine/tenofovir
- Tenofovir Disoproxil Fumarate Drug Combination Emtricitabine. In: Wikidata. https://www.wikidata.org/wiki/Q2412859
- Tenofovir Disoproxil Fumarate Drug Combination Emtricitabine. In: PubChem Compound. CID 11954236. https://pubchem.ncbi.nlm.nih.gov/compound/11954236