Chemicals and Drugs

Taurolithocholic Acid

A bile salt formed in the liver from lithocholic acid conjugation with taurine, usually as the sodium salt. It solubilizes fats for absorption and is itself absorbed. It is a cholagogue and choleretic.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A bile salt formed in the liver from lithocholic acid conjugation with taurine, usually as the sodium salt. It solubilizes fats for absorption and is itself absorbed. It is a cholagogue and choleretic.

Chemical Identity

Chemical Information

Molecular Formula
C26H45NO5S
Molecular Weight
483.7 g/mol
CAS Registry No.
516-90-5
IUPAC Name
2-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid
InChIKey
QBYUNVOYXHFVKC-GBURMNQMSA-N
SMILES
C[C@H](CCC(=O)NCCS(=O)(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)C
MeSH Unique ID
D013658
Source
PubChem CID 439763

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • Lithocholyltaurine
  • Acid, Taurolithocholic
  • Taurine Lithocholate
  • Taurolithocholate
  • Taurolithocholic Acid, Monosodium Salt
  • Lithocholate, Taurine

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

/biosyn /physiol permitted

MeSH Record

History Note

91(78); was see under LITHOCHOLIC ACID 1978-90

MeSH Record

Previous Indexing

  • Bile Acids and Salts (1966-1972)
  • Lithocholic Acid (1973-1977)
  • Taurine (1966-1972)
  • Taurocholic Acid (1973-1977)

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.326.146w.100.850w.875w.925w
  2. D02w.886w.645.600w.055.850w.800w.925w
  3. D04w.210.500w.105w.225.480w.880w
  4. D04w.210.500w.105w.225.900w.920w
  5. D04w.210.500w.221.430.622w.900w
  6. D04w.210.500w.221.430.873w.940w

AMA Style

References

  1. National Library of Medicine. Taurolithocholic Acid. Medical Subject Headings (MeSH). 2026. Unique ID D013658. http://id.nlm.nih.gov/mesh/2026/D013658
  2. Taurolithocholic Acid. In: Wikipedia. https://en.wikipedia.org/wiki/Taurolithocholic_acid
  3. Taurolithocholic Acid. In: Wikidata. https://www.wikidata.org/wiki/Q7688897
  4. Taurolithocholic Acid. In: PubChem Compound. CID 439763. https://pubchem.ncbi.nlm.nih.gov/compound/439763