Chemicals and Drugs

Taurocholic Acid

The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.

Chemical Identity

Chemical Information

Molecular Formula
C26H45NO7S
Molecular Weight
515.7 g/mol
CAS Registry No.
81-24-3
IUPAC Name
2-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid
InChIKey
WBWWGRHZICKQGZ-HZAMXZRMSA-N
SMILES
C[C@H](CCC(=O)NCCS(=O)(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C
MeSH Unique ID
D013656
Source
PubChem CID 6675

MeSH Record

Classification

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • Cholyltaurine
  • Sodium Taurocholate
  • Taurine Cholate
  • Taurocholate
  • Taurocholate Sodium
  • Taurocholic Acid, (5 alpha)-Isomer
  • Taurocholic Acid, (7 beta)-Isomer
  • Taurocholic Acid, Monolithium Salt
  • Taurocholic Acid, Monosodium Salt
  • Taurocholate, Sodium

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

/biosyn /physiol permitted

MeSH Record

History Note

74(73)

MeSH Record

Previous Indexing

  • Bile Acids and Salts (1966-1972)
  • Taurine (1966-1972)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Taurocholic Acid. Medical Subject Headings (MeSH). 2026. Unique ID D013656. http://id.nlm.nih.gov/mesh/2026/D013656
  2. Taurocholic Acid. In: Wikipedia. https://en.wikipedia.org/wiki/Taurocholic_acid
  3. Taurocholic Acid. In: Wikidata. https://www.wikidata.org/wiki/Q2659931
  4. Taurocholic Acid. In: PubChem Compound. CID 6675. https://pubchem.ncbi.nlm.nih.gov/compound/6675