Chemicals and Drugs

Lithocholic Acid

A bile acid formed from chenodeoxycholate by bacterial action, usually conjugated with glycine or taurine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as cholagogue and choleretic.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A bile acid formed from chenodeoxycholate by bacterial action, usually conjugated with glycine or taurine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as cholagogue and choleretic.

Chemical Identity

Chemical Information

Molecular Formula
C24H40O3
Molecular Weight
376.6 g/mol
CAS Registry No.
434-13-9
IUPAC Name
(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
InChIKey
SMEROWZSTRWXGI-HVATVPOCSA-N
SMILES
C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)C
MeSH Unique ID
D008095
Source
PubChem CID 9903

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

4 entry terms
  • Isolithocholic Acid
  • Acid, Isolithocholic
  • Acid, Lithocholic
  • Lithocholate

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

a bile acid; /biosyn /physiol permitted

MeSH Record

History Note

78(73)

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.105w.225.480w
  2. D04w.210.500w.221.430.622w

AMA Style

References

  1. National Library of Medicine. Lithocholic Acid. Medical Subject Headings (MeSH). 2026. Unique ID D008095. http://id.nlm.nih.gov/mesh/2026/D008095
  2. Lithocholic Acid. In: Wikipedia. https://en.wikipedia.org/wiki/Lithocholic_acid
  3. Lithocholic Acid. In: Wikidata. https://www.wikidata.org/wiki/Q3323035
  4. Lithocholic Acid. In: PubChem Compound. CID 9903. https://pubchem.ncbi.nlm.nih.gov/compound/9903