Chemicals and Drugs

Taurochenodeoxycholic Acid

A bile salt formed in the liver by conjugation of chenodeoxycholate with taurine, usually as the sodium salt. It acts as detergent to solubilize fats in the small intestine and is itself absorbed. It is used as a cholagogue and choleretic.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A bile salt formed in the liver by conjugation of chenodeoxycholate with taurine, usually as the sodium salt. It acts as detergent to solubilize fats in the small intestine and is itself absorbed. It is used as a cholagogue and choleretic.

Chemical Identity

Chemical Information

Molecular Formula
C26H45NO6S
Molecular Weight
499.7 g/mol
CAS Registry No.
516-35-8
IUPAC Name
2-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid
InChIKey
BHTRKEVKTKCXOH-BJLOMENOSA-N
SMILES
C[C@H](CCC(=O)NCCS(=O)(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C
MeSH Unique ID
D013655
Source
PubChem CID 387316

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

5 entry terms
  • Chenodeoxycholyltaurine
  • Acid, Taurochenodeoxycholic
  • Taurine Chenodeoxycholate
  • Taurochenodeoxycholate
  • Chenodeoxycholate, Taurine

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

/biosyn /physiol permitted

MeSH Record

History Note

91(78); was see under CHENODEOXYCHOLIC ACID 1978-90

MeSH Record

Previous Indexing

  • Bile Acids and Salts (1966-1972)
  • Chenodeoxycholic Acid (1973-1977)
  • Taurine (1966-1972)
  • Taurocholic Acid (1973-1977)

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.326.146w.100.850w.875w.900w.875w
  2. D02w.886w.645.600w.055.850w.800w.900w.875w
  3. D04w.210.500w.105w.225.272w.150w.850w
  4. D04w.210.500w.105w.225.272w.925w.875w
  5. D04w.210.500w.105w.225.900w.900w.870w
  6. D04w.210.500w.221.430.342w.300w.900w
  7. D04w.210.500w.221.430.342w.900w.910w
  8. D04w.210.500w.221.430.873w.920w.900w

AMA Style

References

  1. National Library of Medicine. Taurochenodeoxycholic Acid. Medical Subject Headings (MeSH). 2026. Unique ID D013655. http://id.nlm.nih.gov/mesh/2026/D013655
  2. Taurochenodeoxycholic Acid. In: Wikipedia. https://en.wikipedia.org/wiki/Taurochenodeoxycholic_acid
  3. Taurochenodeoxycholic Acid. In: Wikidata. https://www.wikidata.org/wiki/Q7688892
  4. Taurochenodeoxycholic Acid. In: PubChem Compound. CID 387316. https://pubchem.ncbi.nlm.nih.gov/compound/387316