Chemicals and Drugs

Chenodeoxycholic Acid

A bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.

Chemical Identity

Chemical Information

Molecular Formula
C24H40O4
Molecular Weight
392.6 g/mol
CAS Registry No.
474-25-9
IUPAC Name
(4R)-4-[(3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
InChIKey
RUDATBOHQWOJDD-BSWAIDMHSA-N
SMILES
C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C
MeSH Unique ID
D002635
Source
PubChem CID 10133

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

18 entry terms
  • Chenic Acid
  • Chenique Acid
  • Chenodiol
  • Gallodesoxycholic Acid
  • Henohol
  • Acid, Chenic
  • Acid, Chenique
  • Acid, Chenodeoxycholic
  • Acid, Gallodesoxycholic
  • Chenix
  • Chenodeoxycholate
  • Chenofalk
  • Chenophalk
  • Ctexli
  • Quenobilan
  • Quenocol
  • Sodium Chenodeoxycholate
  • Chenodeoxycholate, Sodium

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

74(73)

MeSH Record

Previous Indexing

  • Bile Acids and Salts (1966-1972)

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.105w.225.272w.150w
  2. D04w.210.500w.221.430.342w.300w

AMA Style

References

  1. National Library of Medicine. Chenodeoxycholic Acid. Medical Subject Headings (MeSH). 2026. Unique ID D002635. http://id.nlm.nih.gov/mesh/2026/D002635
  2. Chenodeoxycholic Acid. In: Wikipedia. https://en.wikipedia.org/wiki/Chenodeoxycholic_acid
  3. Chenodeoxycholic Acid. In: Wikidata. https://www.wikidata.org/wiki/Q419028
  4. Chenodeoxycholic Acid. In: PubChem Compound. CID 10133. https://pubchem.ncbi.nlm.nih.gov/compound/10133