Structured Summary
Abstract
A family of structurally related proteins that are induced by CYTOKINES and negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. SOCS proteins contain a central SH2 DOMAIN and a C-terminal region of homology known as the SOCS box.
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Synonyms
5 entry terms
- SOCS Proteins
- Suppressors of Cytokine Signaling Proteins
- Cytokine Inducible SH2-Containing Protein
- SOCS Protein
- Suppressor of Cytokine Signaling Protein
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2026 (2006)
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References
- National Library of Medicine. Suppressor of Cytokine Signaling Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D050826. http://id.nlm.nih.gov/mesh/2026/D050826
- Suppressor of Cytokine Signaling Proteins. In: Wikipedia. https://en.wikipedia.org/wiki/Suppressor_of_cytokine_signalling
- Suppressor of Cytokine Signaling Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q7644655