Chemicals and Drugs

Smad Proteins

A family of proteins that are involved in the translocation of signals from TGF-BETA RECEPTORS; BONE MORPHOGENETIC PROTEIN RECEPTORS; and other surface receptors to the CELL NUCLEUS. They were originally identified as a class of proteins that are related to the mothers against decapentaplegic protein, Drosophila and sma proteins from CAENORHABDITIS ELEGANS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of proteins that are involved in the translocation of signals from TGF-BETA RECEPTORS; BONE MORPHOGENETIC PROTEIN RECEPTORS; and other surface receptors to the CELL NUCLEUS. They were originally identified as a class of proteins that are related to the mothers against decapentaplegic protein, Drosophila and sma proteins from CAENORHABDITIS ELEGANS.

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MeSH Record

Synonyms

2 entry terms
  • Mothers Against Decapentaplegic Homolog
  • Sma- and Mad-Related Proteins

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

general; prefer specifics

MeSH Record

History Note

2006(1996)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.360.024w.334w
  2. D12.776w.157w.057w.170w
  3. D12.776w.260w.713w
  4. D12.776w.476.024w.428w
  5. D12.776w.930w.806w

AMA Style

References

  1. National Library of Medicine. Smad Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D051785. http://id.nlm.nih.gov/mesh/2026/D051785
  2. Smad Proteins. In: Wikipedia. https://en.wikipedia.org/wiki/SMAD_(protein)
  3. Smad Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q700000