Chemicals and Drugs

Inhibitory Smad Proteins

A sub-family of smad proteins that inhibit cell signaling by RECEPTOR-REGULATED SMAD PROTEINS. They form autoinhibitory feedback loops in the TGF-BETA signaling pathway and mediate signaling cross-talk with other signaling pathways

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A sub-family of smad proteins that inhibit cell signaling by RECEPTOR-REGULATED SMAD PROTEINS. They form autoinhibitory feedback loops in the TGF-BETA signaling pathway and mediate signaling cross-talk with other signaling pathways

MeSH Record

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MeSH Record

Synonyms

2 entry terms
  • I-Smad Proteins
  • Smad Proteins, Inhibitory

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006

MeSH Hierarchy

Tree Numbers

  1. D12.644w.360.024w.334w.200w
  2. D12.776w.157w.057w.170w.249w
  3. D12.776w.476.024w.428w.249w

AMA Style

References

  1. National Library of Medicine. Inhibitory Smad Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D051897. http://id.nlm.nih.gov/mesh/2026/D051897
  2. Inhibitory Smad Proteins. In: Wikipedia. https://en.wikipedia.org/wiki/I-SMAD
  3. Inhibitory Smad Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q5967671