Chemicals and Drugs

Smad4 Protein

A signal transducing adaptor protein and tumor suppressor protein. It forms a complex with activated RECEPTOR-REGULATED SMAD PROTEINS. The complex then translocates to the CELL NUCLEUS and regulates GENETIC TRANSCRIPTION of target GENES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A signal transducing adaptor protein and tumor suppressor protein. It forms a complex with activated RECEPTOR-REGULATED SMAD PROTEINS. The complex then translocates to the CELL NUCLEUS and regulates GENETIC TRANSCRIPTION of target GENES.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

3 entry terms
  • Common Smad
  • MADH4 Protein
  • Smad, Common

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1996)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.360.024w.334w.750w
  2. D12.776w.157w.057w.170w.750w
  3. D12.776w.260w.713w.750w
  4. D12.776w.476.024w.428w.750w
  5. D12.776w.624.776.760w
  6. D12.776w.930w.806w.750w

AMA Style

References

  1. National Library of Medicine. Smad4 Protein. Medical Subject Headings (MeSH). 2026. Unique ID D051901. http://id.nlm.nih.gov/mesh/2026/D051901
  2. Smad4 Protein. In: Wikipedia. https://en.wikipedia.org/wiki/SMAD4
  3. Smad4 Protein. In: Wikidata. https://www.wikidata.org/wiki/Q408179