Structured Summary
Abstract
A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-6 family members. STAT3 is constitutively activated in a variety of TUMORS and is a major downstream transducer for the CYTOKINE RECEPTOR GP130.
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Synonyms
20 entry terms
- APRF Transcription Factor
- Acute-Phase Response Factor
- IL6-Response Factor
- LIF-Response Factor
- STAT3 Protein
- Signal Transducer and Activator of Transcription 3
- Acute Phase Response Factor
- IL6 Response Factor
- LIF Response Factor
- Response Factor, Acute-Phase
- Transcription Factor, APRF
- Transcription Factor, STAT3
- STAT3a Transcription Factor
- STAT3b Transcription Factor
- Stat3alpha Transcription Factor
- Stat3beta Transcription Factor
- Transcription Factor, STAT3a
- Transcription Factor, STAT3b
- Transcription Factor, Stat3alpha
- Transcription Factor, Stat3beta
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. STAT3 Transcription Factor. Medical Subject Headings (MeSH). 2026. Unique ID D050796. http://id.nlm.nih.gov/mesh/2026/D050796
- STAT3 Transcription Factor. In: Wikidata. https://www.wikidata.org/wiki/Q4210010