Chemicals and Drugs

Ranibizumab

A recombinant humanized monoclonal antibody fragment that binds VEGF-A to prevent its binding to VEGFR-1 and VEGFR-2 receptors. This activity reduces vessel permeability and angiogenesis in the treatment of neovascular age-related MACULAR DEGENERATION.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A recombinant humanized monoclonal antibody fragment that binds VEGF-A to prevent its binding to VEGFR-1 and VEGFR-2 receptors. This activity reduces vessel permeability and angiogenesis in the treatment of neovascular age-related MACULAR DEGENERATION.

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

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See Also

MeSH Record

Synonyms

3 entry terms
  • RhuFab V2
  • V2, RhuFab
  • Lucentis

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2016 (2005)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.124w.486.485.114w.224w.060w.868w
  2. D12.776w.124w.790.651.114w.224w.060w.868w
  3. D12.776w.377w.715.548.114w.224w.200w.868w

AMA Style

References

  1. National Library of Medicine. Ranibizumab. Medical Subject Headings (MeSH). 2026. Unique ID D000069579. http://id.nlm.nih.gov/mesh/2026/D000069579
  2. Ranibizumab. In: Wikipedia. https://en.wikipedia.org/wiki/Ranibizumab
  3. Ranibizumab. In: Wikidata. https://www.wikidata.org/wiki/Q414270