Structured Summary
Abstract
An inhibitory T-lymphocyte receptor that has specificity for CD274 ANTIGEN and PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN. Signaling by the receptor limits T cell proliferation and INTERFERON GAMMA synthesis. The receptor also may play an essential role in the regulatory pathway that induces PERIPHERAL TOLERANCE.
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Synonyms
13 entry terms
- Antigens, CD279
- CD279 Antigen
- PD-1 Protein
- PD-1 Receptor
- PD1 Receptor
- Programmed Cell Death 1 Protein
- Programmed Cell Death Protein 1
- Antigen, CD279
- CD279 Antigens
- PD 1 Protein
- PD 1 Receptor
- Receptor, PD-1
- Receptor, PD1
MeSH Record
Aspects Covered
19 allowable subheadings
Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.
MeSH Record
History Note
2012
MeSH Record
Previous Indexing
- Antigens, CD (1997-2011)
- Antigens, Surface (1997-2006)
- Apoptosis Regulatory Proteins (1977-2011)
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AMA Style
References
- National Library of Medicine. Programmed Cell Death 1 Receptor. Medical Subject Headings (MeSH). 2026. Unique ID D061026. http://id.nlm.nih.gov/mesh/2026/D061026
- Programmed Cell Death 1 Receptor. In: Wikipedia. https://en.wikipedia.org/wiki/Programmed_cell_death_protein_1
- Programmed Cell Death 1 Receptor. In: Wikidata. https://www.wikidata.org/wiki/Q21208025