Chemicals and Drugs

Patched Receptors

A family of 12-pass transmembrane proteins originally identified in Drosophila that are receptors for HEDGEHOG PROTEINS. They have important roles in regulating CELL PROLIFERATION; CELL DIFFERENTIAION; and BODY PATTERNING and may also function as TUMOR SUPPRESSOR PROTEINS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of 12-pass transmembrane proteins originally identified in Drosophila that are receptors for HEDGEHOG PROTEINS. They have important roles in regulating CELL PROLIFERATION; CELL DIFFERENTIAION; and BODY PATTERNING and may also function as TUMOR SUPPRESSOR PROTEINS.

MeSH Record

Classification

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MeSH Record

Synonyms

5 entry terms
  • Patched Protein
  • Patched Receptor
  • Patched Sonic Hedgehog Receptors
  • Receptor, Patched
  • Receptors, Patched

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2017 (1996)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.543w.750w.058
  2. D12.776w.624.776.633

AMA Style

References

  1. National Library of Medicine. Patched Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D000072079. http://id.nlm.nih.gov/mesh/2026/D000072079
  2. Patched Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q76543892