Chemicals and Drugs

Patched-2 Receptor

A patched receptor that may function redundantly with the PATCHED-1 RECEPTOR to modulate hedgehog signaling. It may also play a role in epidermal development and as a TUMOR SUPPRESSOR PROTEIN. Mutations in the patched-2 gene are associated with BASAL CELL NEVUS SYNDROME; BASAL CELL CARCINOMA; and MEDULLOBLASTOMA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A patched receptor that may function redundantly with the PATCHED-1 RECEPTOR to modulate hedgehog signaling. It may also play a role in epidermal development and as a TUMOR SUPPRESSOR PROTEIN. Mutations in the patched-2 gene are associated with BASAL CELL NEVUS SYNDROME; BASAL CELL CARCINOMA; and MEDULLOBLASTOMA.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

9 entry terms
  • PTCH2 Protein
  • Patched Homolog-2
  • Patched Receptor-2
  • Patched-2 Protein
  • Patched 2 Protein
  • Patched 2 Receptor
  • Patched Homolog 2
  • Patched Receptor 2
  • Receptor, Patched-2

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2017 (1996)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.543w.750w.058.750
  2. D12.776w.624.776.633.750

AMA Style

References

  1. National Library of Medicine. Patched-2 Receptor. Medical Subject Headings (MeSH). 2026. Unique ID D000072082. http://id.nlm.nih.gov/mesh/2026/D000072082
  2. Patched-2 Receptor. In: Wikidata. https://www.wikidata.org/wiki/Q21135201