Structured Summary
Abstract
A patched receptor for several HEDGEHOG PROTEINS that associates with the SMOOTHENED RECEPTOR to modulate hedgehog signaling. It is also a TUMOR SUPPRESSOR PROTEIN; mutations in the patched-1 gene are associated with BASAL CELL NEVUS SYNDROME; SQUAMOUS CELL CARCNIOMA of the ESOPHAGUS; trichoepitheliomas, and CARCINOMA, TRANSITIONAL CELL of the URINARY BLADDER.
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
Synonyms
10 entry terms
- PTCH1 Protein
- Patched Homolog-1
- Patched Receptor-1
- Patched-1 Protein
- Patched 1 Protein
- Patched 1 Receptor
- Patched Homolog 1
- Patched Receptor 1
- Receptor, Patched-1
- Receptor-1, Patched
MeSH Record
Aspects Covered
19 allowable subheadings
Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.
MeSH Record
History Note
2017 (1996)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Patched-1 Receptor. Medical Subject Headings (MeSH). 2026. Unique ID D000072081. http://id.nlm.nih.gov/mesh/2026/D000072081
- Patched-1 Receptor. In: Wikidata. https://www.wikidata.org/wiki/Q58623120