Chemicals and Drugs

Lypressin

The porcine antidiuretic hormone (VASOPRESSINS). It is a cyclic nonapeptide that differs from ARG-VASOPRESSIN by one amino acid, containing a LYSINE at residue 8 instead of an ARGININE. Lys-vasopressin is used to treat DIABETES INSIPIDUS or to improve vasomotor tone and BLOOD PRESSURE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The porcine antidiuretic hormone (VASOPRESSINS). It is a cyclic nonapeptide that differs from ARG-VASOPRESSIN by one amino acid, containing a LYSINE at residue 8 instead of an ARGININE. Lys-vasopressin is used to treat DIABETES INSIPIDUS or to improve vasomotor tone and BLOOD PRESSURE.

Chemical Identity

Chemical Information

Molecular Formula
C46H65N13O12S2
Molecular Weight
1056.2 g/mol
IUPAC Name
N-[6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]-1-[19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
InChIKey
BJFIDCADFRDPIO-UHFFFAOYSA-N
SMILES
C1CC(N(C1)C(=O)C2CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)NC(CCCCN)C(=O)NCC(=O)N
MeSH Unique ID
D008236
Source
PubChem CID 5772

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

11 entry terms
  • 8-Lysine Vasopressin
  • Lys-Vasopressin
  • Lysine Vasopressin
  • Lysyl Vasopressin
  • Vasopressin, Lysine
  • 8 Lysine Vasopressin
  • Lys Vasopressin
  • Vasopressin, 8-Lysine
  • Vasopressin, Lysyl
  • Diapid
  • Postacton

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2010, 1979-2006 (1975)

MeSH Record

Previous Indexing

  • Lysine (1966-1974)
  • Vasopressins (1966-1974)

MeSH Hierarchy

Tree Numbers

  1. D06.472w.699w.631.692.781.400
  2. D12.644w.400w.900.400
  3. D12.644w.456w.925.480
  4. D12.644w.548w.691.692.781.400
  5. D12.776w.631w.650w.937.400

MeSH Record

NLM Classification

WK 520

AMA Style

References

  1. National Library of Medicine. Lypressin. Medical Subject Headings (MeSH). 2026. Unique ID D008236. http://id.nlm.nih.gov/mesh/2026/D008236
  2. Lypressin. In: Wikidata. https://www.wikidata.org/wiki/Q27107266
  3. Lypressin. In: PubChem Compound. CID 5772. https://pubchem.ncbi.nlm.nih.gov/compound/5772