Chemicals and Drugs

Felypressin

A synthetic analog of LYPRESSIN with a PHENYLALANINE substitution at residue 2. Felypressin is a vasoconstrictor with reduced antidiuretic activity.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A synthetic analog of LYPRESSIN with a PHENYLALANINE substitution at residue 2. Felypressin is a vasoconstrictor with reduced antidiuretic activity.

Chemical Identity

Chemical Information

Molecular Formula
C46H65N13O11S2
Molecular Weight
1040.2 g/mol
CAS Registry No.
56-59-7
IUPAC Name
(2S)-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13,16-dibenzyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
InChIKey
SFKQVVDKFKYTNA-DZCXQCEKSA-N
SMILES
C1C[C@H](N(C1)C(=O)[C@@H]2CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=CC=C4)N)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N
MeSH Unique ID
D005259
Source
PubChem CID 14257662

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • Octapressin
  • Octopressin
  • PLV-2
  • Phelypressin
  • Phenylalanine Lysine Vasopressin
  • Vasopressin, Phenylalanyl-Lysyl
  • Lysine Vasopressin, Phenylalanine
  • Phenylalanyl-Lysyl Vasopressin
  • Vasopressin, Phenylalanine Lysine
  • Vasopressin, Phenylalanyl Lysyl

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(79); was see under LYPRESSIN 1979-90; was PHELYPRESSIN see under VASOPRESSIN 1965-78 (Prov 1965-74)

MeSH Hierarchy

Tree Numbers

  1. D06.472w.699w.631.692.781.400.350w
  2. D12.644w.400w.900.400.350w
  3. D12.644w.456w.925.480.500w
  4. D12.644w.548w.691.692.781.400.350w
  5. D12.776w.631w.650w.937.400.350w

AMA Style

References

  1. National Library of Medicine. Felypressin. Medical Subject Headings (MeSH). 2026. Unique ID D005259. http://id.nlm.nih.gov/mesh/2026/D005259
  2. Felypressin. In: Wikipedia. https://en.wikipedia.org/wiki/Felypressin
  3. Felypressin. In: Wikidata. https://www.wikidata.org/wiki/Q5442706
  4. Felypressin. In: PubChem Compound. CID 14257662. https://pubchem.ncbi.nlm.nih.gov/compound/14257662