Chemicals and Drugs

Group C Member 2 Nuclear Receptor Subfamily 2

An orphan nuclear receptor that has specificity for hormone response elements found in the promoters of target genes. It binds DNA either as a homodimer or as heterodimer with the closely-related orphan nuclear receptor NUCLEAR RECEPTOR SUBFAMILY 2, GROUP C, MEMBER 1. The protein was originally identified as a TESTES-specific protein and is involved in the regulation of variety of cellular processes, including CELL DIFFERENTIATION; CELL PROLIFERATION; and APOPTOSIS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An orphan nuclear receptor that has specificity for hormone response elements found in the promoters of target genes. It binds DNA either as a homodimer or as heterodimer with the closely-related orphan nuclear receptor NUCLEAR RECEPTOR SUBFAMILY 2, GROUP C, MEMBER 1. The protein was originally identified as a TESTES-specific protein and is involved in the regulation of variety of cellular processes, including CELL DIFFERENTIATION; CELL PROLIFERATION; and APOPTOSIS.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

8 entry terms
  • Nuclear Receptor NR2C2
  • Nuclear Receptor Subfamily 2, Group C, Member 2
  • Orphan Nuclear Receptor TR4
  • TAK1 Receptor
  • TR4 Nuclear Hormone Receptor
  • Testicular Receptor 4
  • NR2C2, Nuclear Receptor
  • Receptor, TAK1

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2010

MeSH Record

Previous Indexing

  • Receptors, Steroid (2004-2009)
  • Receptors, Thyroid Hormone (2004-2009)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Group C Member 2 Nuclear Receptor Subfamily 2. Medical Subject Headings (MeSH). 2026. Unique ID D057125. http://id.nlm.nih.gov/mesh/2026/D057125
  2. Group C Member 2 Nuclear Receptor Subfamily 2. In: Wikidata. https://www.wikidata.org/wiki/Q21120955