Structured Summary
Abstract
A DNA-binding orphan nuclear receptor that has specificity for directly repeated (DR) AGGTCA sequences. It binds DNA as either as a homodimer or as a heterodimer with the closely-related orphan nuclear receptor NUCLEAR RECEPTOR SUBFAMILY 2, GROUP C, MEMBER 2. The protein was originally identified as a PROSTATE-specific protein and is involved in the regulation of variety of cellular processes, including CELL DIFFERENTIATION; CELL PROLIFERATION; and APOPTOSIS.
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Classification
Broader headings
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MeSH Record
Synonyms
8 entry terms
- Nuclear Receptor NR2C1
- Nuclear Receptor Subfamily 2, Group C, Member 1
- Nuclear Receptor TR2
- Orphan Nuclear Receptor NR2C1
- Orphan Nuclear Receptor TR2
- TR2-11 Receptor
- Receptor TR2, Nuclear
- TR2 11 Receptor
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2010(1995)
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References
- National Library of Medicine. Group C Member 1 Nuclear Receptor Subfamily 2. Medical Subject Headings (MeSH). 2026. Unique ID D057107. http://id.nlm.nih.gov/mesh/2026/D057107
- Group C Member 1 Nuclear Receptor Subfamily 2. In: Wikidata. https://www.wikidata.org/wiki/Q21120953