Chemicals and Drugs

Group A Member 1 Nuclear Receptor Subfamily 4

An orphan nuclear receptor that is closely related to members of the thyroid-steroid receptor gene family. It was originally identified in NERVE CELLS and may play a role in mediation of NERVE GROWTH FACTOR-induced CELL DIFFERENTIATION. However, several other functions have been attributed to this protein including the positive and negative regulation of APOPTOSIS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An orphan nuclear receptor that is closely related to members of the thyroid-steroid receptor gene family. It was originally identified in NERVE CELLS and may play a role in mediation of NERVE GROWTH FACTOR-induced CELL DIFFERENTIATION. However, several other functions have been attributed to this protein including the positive and negative regulation of APOPTOSIS.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

14 entry terms
  • Early Response Protein NAK1
  • NGFI-B Orphan Nuclear Receptor
  • Nerve Growth Factor-inducible B Protein
  • Nuclear Receptor NR4A1
  • Nuclear Receptor Subfamily 4, Group A, Member 1
  • Nur77 Orphan Nuclear Receptor
  • Orphan Nuclear Receptor HMR
  • Orphan Nuclear Receptor NGFI-B
  • Orphan Nuclear Receptor NR4A1
  • Orphan Nuclear Receptor TR3
  • TR3 Orphan Nuclear Receptor
  • NGFI B Orphan Nuclear Receptor
  • Nerve Growth Factor inducible B Protein
  • Orphan Nuclear Receptor NGFI B

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2010(1991)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.260w.643w.400w
  2. D12.776w.826w.209w.400w

AMA Style

References

  1. National Library of Medicine. Group A Member 1 Nuclear Receptor Subfamily 4. Medical Subject Headings (MeSH). 2026. Unique ID D057105. http://id.nlm.nih.gov/mesh/2026/D057105
  2. Group A Member 1 Nuclear Receptor Subfamily 4. In: Wikipedia. https://en.wikipedia.org/wiki/Nuclear_receptor_4A1
  3. Group A Member 1 Nuclear Receptor Subfamily 4. In: Wikidata. https://www.wikidata.org/wiki/Q12063746