Chemicals and Drugs

Glycochenodeoxycholic Acid

A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.

Chemical Identity

Chemical Information

Molecular Formula
C26H43NO5
Molecular Weight
449.6 g/mol
CAS Registry No.
640-79-9
IUPAC Name
2-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid
InChIKey
GHCZAUBVMUEKKP-GYPHWSFCSA-N
SMILES
C[C@H](CCC(=O)NCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C
MeSH Unique ID
D005999
Source
PubChem CID 12544

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

5 entry terms
  • Chenodeoxycholylglycine
  • Acid, Glycochenodeoxycholic
  • Glycine Chenodeoxycholate
  • Glycochenodeoxycholate
  • Chenodeoxycholate, Glycine

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

a bile acid; /biosyn /physiol permitted

MeSH Record

History Note

91(78); was see under CHENODEOXYCHOLIC ACID 1978-90

MeSH Record

Previous Indexing

  • Bile Acids and Salts (1966-1972)
  • Chenodeoxycholic Acid (1973-1977)
  • Glycine (1966-1972)
  • Glycocholic Acid (1973-1977)

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.105w.225.272w.150w.350w
  2. D04w.210.500w.105w.225.272w.411w.360w
  3. D04w.210.500w.105w.225.400w.380w.360w
  4. D04w.210.500w.221.430.342w.300w.400w
  5. D04w.210.500w.221.430.342w.400w.450w
  6. D04w.210.500w.221.430.484w.430w.420w
  7. D12.125w.481w.700.249w.420w.400w

AMA Style

References

  1. National Library of Medicine. Glycochenodeoxycholic Acid. Medical Subject Headings (MeSH). 2026. Unique ID D005999. http://id.nlm.nih.gov/mesh/2026/D005999
  2. Glycochenodeoxycholic Acid. In: Wikipedia. https://en.wikipedia.org/wiki/Glycochenodeoxycholic_acid
  3. Glycochenodeoxycholic Acid. In: Wikidata. https://www.wikidata.org/wiki/Q5572600
  4. Glycochenodeoxycholic Acid. In: PubChem Compound. CID 12544. https://pubchem.ncbi.nlm.nih.gov/compound/12544