Diseases

Gardner Syndrome

A variant of ADENOMATOUS POLYPOSIS COLI caused by mutation in the APC gene (GENES, APC) on CHROMOSOME 5. It is characterized by not only the presence of multiple colonic polyposis but also extracolonic ADENOMATOUS POLYPS in the UPPER GASTROINTESTINAL TRACT; the EYE; the SKIN; the SKULL; and the FACIAL BONES; as well as malignancy in organs other than the GI tract.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A variant of ADENOMATOUS POLYPOSIS COLI caused by mutation in the APC gene (GENES, APC) on CHROMOSOME 5. It is characterized by not only the presence of multiple colonic polyposis but also extracolonic ADENOMATOUS POLYPS in the UPPER GASTROINTESTINAL TRACT; the EYE; the SKIN; the SKULL; and the FACIAL BONES; as well as malignancy in organs other than the GI tract.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

See Also

MeSH Record

Synonyms

8 entry terms
  • Gardner's Syndrome
  • Gardner Syndromes
  • Gardner's Syndromes
  • Gardners Syndrome
  • Syndrome, Gardner
  • Syndrome, Gardner's
  • Syndromes, Gardner
  • Syndromes, Gardner's

MeSH Record

Aspects Covered

39 allowable subheadings

Indexed with the subheadings blood, blood supply, cerebrospinal fluid, chemically induced, chemistry, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, secondary, surgery, therapy, ultrastructure, urine, veterinary, virology.

MeSH Record

History Note

1981

MeSH Record

Previous Indexing

  • Colonic Neoplasms (1966-1980)
  • Intestinal Polyps/FG (1968-1980)
  • Neoplasms, Multiple Primary (1966-1980)

MeSH Hierarchy

Tree Numbers

  1. C04w.557.470.035w.215w.100w.500w
  2. C04w.588.274.476.411w.307.089w.393w
  3. C04w.700w.100w.392w
  4. C06w.301.371.411w.307.090w.500w
  5. C06w.405w.249.411w.307.090w.500w
  6. C06w.405w.469w.158.356.090w.500w
  7. C06w.405w.469w.491w.307.090w.500w
  8. C06w.405w.469w.578w.249w.393w
  9. C16w.131w.077w.393w
  10. C16w.320w.700w.100w.393w

AMA Style

References

  1. National Library of Medicine. Gardner Syndrome. Medical Subject Headings (MeSH). 2026. Unique ID D005736. http://id.nlm.nih.gov/mesh/2026/D005736
  2. Gardner Syndrome. In: Wikipedia. https://en.wikipedia.org/wiki/Gardner%27s_syndrome
  3. Gardner Syndrome. In: Wikidata. https://www.wikidata.org/wiki/Q1702335