Phenomena and Processes

APC Genes

Tumor suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (ADENOMATOUS POLYPOSIS COLI) and GARDNER SYNDROME, as well as some sporadic colorectal cancers.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Tumor suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (ADENOMATOUS POLYPOSIS COLI) and GARDNER SYNDROME, as well as some sporadic colorectal cancers.

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Classification

Broader headings

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See Also

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Synonyms

4 entry terms
  • Genes, APC
  • Genes, Adenomatous Polyposis Coli
  • APC Gene
  • Gene, APC

MeSH Record

Aspects Covered

4 allowable subheadings

Indexed with the subheadings drug effects, ethics, physiology, radiation effects.

MeSH Record

History Note

93

MeSH Record

Previous Indexing

  • Genes, Suppressor, Tumor (1991-1992)
  • Polyposis Syndrome, Familial/genetics (1989-1992)

MeSH Hierarchy

Tree Numbers

  1. G05.360w.340w.024.340w.375.249w.050w
  2. G05.360w.340w.024.340w.415.400w.050w

AMA Style

References

  1. National Library of Medicine. APC Genes. Medical Subject Headings (MeSH). 2026. Unique ID D017491. http://id.nlm.nih.gov/mesh/2026/D017491
  2. APC Genes. In: Wikipedia. https://en.wikipedia.org/wiki/Adenomatous_polyposis_coli
  3. APC Genes. In: Wikidata. https://www.wikidata.org/wiki/Q14883378