Chemicals and Drugs

Connective Tissue Growth Factor

A CCN protein family member that regulates a variety of extracellular functions including CELL ADHESION; CELL MIGRATION; and EXTRACELLULAR MATRIX synthesis. It is found in hypertrophic CHONDROCYTES where it may play a role in CHONDROGENESIS and endochondral ossification.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A CCN protein family member that regulates a variety of extracellular functions including CELL ADHESION; CELL MIGRATION; and EXTRACELLULAR MATRIX synthesis. It is found in hypertrophic CHONDROCYTES where it may play a role in CHONDROGENESIS and endochondral ossification.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

9 entry terms
  • CCN2 Protein
  • Hypertrophic Chondrocyte-Specific Protein 24
  • IGF-Binding Protein-Related Protein-2
  • IGFBP-8
  • IGFBP-rP2
  • Insulin-Like Growth Factor Binding Protein 8
  • Hypertrophic Chondrocyte Specific Protein 24
  • IGF Binding Protein Related Protein 2
  • Insulin Like Growth Factor Binding Protein 8

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2009(1991)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Connective Tissue Growth Factor. Medical Subject Headings (MeSH). 2026. Unique ID D055513. http://id.nlm.nih.gov/mesh/2026/D055513
  2. Connective Tissue Growth Factor. In: Wikidata. https://www.wikidata.org/wiki/Q5014566