Chemicals and Drugs

CCN Intercellular Signaling Proteins

A family of secreted proteins found associated with the EXTRACELLULAR MATRIX and cell surface receptors. They are believed to play a role in modulating the effects of a variety of GROWTH FACTORS and PROTEASES at the cell membrane extracellular matrix. The CCN protein family is named after three protypical members; CYSTEINE-RICH PROTEIN 61; CONNECTIVE TISSUE GROWTH FACTOR; and NEPHROBLASTOMA OVEREXPRESSED PROTEIN.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of secreted proteins found associated with the EXTRACELLULAR MATRIX and cell surface receptors. They are believed to play a role in modulating the effects of a variety of GROWTH FACTORS and PROTEASES at the cell membrane extracellular matrix. The CCN protein family is named after three protypical members; CYSTEINE-RICH PROTEIN 61; CONNECTIVE TISSUE GROWTH FACTOR; and NEPHROBLASTOMA OVEREXPRESSED PROTEIN.

MeSH Record

Classification

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MeSH Record

Synonyms

3 entry terms
  • CCN Family Proteins
  • CYR61 CTGF NOV Matricellular Proteins
  • Matricellular CCN Proteins

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2009

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AMA Style

References

  1. National Library of Medicine. CCN Intercellular Signaling Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D055511. http://id.nlm.nih.gov/mesh/2026/D055511
  2. CCN Intercellular Signaling Proteins. In: Wikipedia. https://en.wikipedia.org/wiki/CCN_protein
  3. CCN Intercellular Signaling Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q24744951