Chemicals and Drugs

Betamethasone

A glucocorticoid given orally, parenterally, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. Its lack of mineralocorticoid properties makes betamethasone particularly suitable for treating cerebral edema and congenital adrenal hyperplasia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p724)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A glucocorticoid given orally, parenterally, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. Its lack of mineralocorticoid properties makes betamethasone particularly suitable for treating cerebral edema and congenital adrenal hyperplasia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p724)

Chemical Identity

Chemical Information

Molecular Formula
C22H29FO5
Molecular Weight
392.5 g/mol
CAS Registry No.
378-44-9
IUPAC Name
(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
InChIKey
UREBDLICKHMUKA-DVTGEIKXSA-N
SMILES
C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C
MeSH Unique ID
D001623
Source
PubChem CID 9782

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • Betadexamethasone
  • Flubenisolone
  • Celeston
  • Celestona
  • Celestone
  • Cellestoderm

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

64(63)

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.745.432w.769.199w
  2. D04w.210.500w.908.093w

MeSH Record

NLM Classification

WK 755

AMA Style

References

  1. National Library of Medicine. Betamethasone. Medical Subject Headings (MeSH). 2026. Unique ID D001623. http://id.nlm.nih.gov/mesh/2026/D001623
  2. Betamethasone. In: Wikipedia. https://en.wikipedia.org/wiki/Betamethasone
  3. Betamethasone. In: Wikidata. https://www.wikidata.org/wiki/Q416132
  4. Betamethasone. In: PubChem Compound. CID 9782. https://pubchem.ncbi.nlm.nih.gov/compound/9782