Chemicals and Drugs

Betamethasone Valerate

The 17-valerate derivative of BETAMETHASONE. It has substantial topical anti-inflammatory activity and relatively low systemic anti-inflammatory activity.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The 17-valerate derivative of BETAMETHASONE. It has substantial topical anti-inflammatory activity and relatively low systemic anti-inflammatory activity.

Chemical Identity

Chemical Information

Molecular Formula
C27H37FO6
Molecular Weight
476.6 g/mol
CAS Registry No.
2152-44-5
IUPAC Name
[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] pentanoate
InChIKey
SNHRLVCMMWUAJD-SUYDQAKGSA-N
SMILES
CCCCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)C(=O)CO
MeSH Unique ID
D001624
Source
PubChem CID 16533

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • Betamethasone 17-Valerate
  • Flubenisolonvalerate
  • 17-Valerate, Betamethasone
  • Betamethasone 17 Valerate
  • Valerate, Betamethasone
  • Betnovate

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(76); was see under BETAMETHASONE 1976-90

MeSH Record

Previous Indexing

  • Betamethasone (1974) /AA (1975)
  • Valerates (1974-1975)

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.745.432w.769.199w.150w
  2. D04w.210.500w.908.093w.150w

AMA Style

References

  1. National Library of Medicine. Betamethasone Valerate. Medical Subject Headings (MeSH). 2026. Unique ID D001624. http://id.nlm.nih.gov/mesh/2026/D001624
  2. Betamethasone Valerate. In: Wikipedia. https://en.wikipedia.org/wiki/Betamethasone_valerate
  3. Betamethasone Valerate. In: Wikidata. https://www.wikidata.org/wiki/Q6445931
  4. Betamethasone Valerate. In: PubChem Compound. CID 16533. https://pubchem.ncbi.nlm.nih.gov/compound/16533