Chemicals and Drugs

Arachidonate Lipoxygenases

Enzymes catalyzing the oxidation of arachidonic acid to hydroperoxyarachidonates. These products are then rapidly converted by a peroxidase to hydroxyeicosatetraenoic acids. The positional specificity of the enzyme reaction varies from tissue to tissue. The final lipoxygenase pathway leads to the leukotrienes. EC 1.13.11.- .

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Enzymes catalyzing the oxidation of arachidonic acid to hydroperoxyarachidonates. These products are then rapidly converted by a peroxidase to hydroxyeicosatetraenoic acids. The positional specificity of the enzyme reaction varies from tissue to tissue. The final lipoxygenase pathway leads to the leukotrienes. EC 1.13.11.- .

MeSH Record

Classification

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MeSH Record

Synonyms

3 entry terms
  • Arachidonic Acid Lipoxygenase
  • Lipoxygenase, Arachidonic Acid
  • Lipoxygenases, Arachidonate

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

87

MeSH Record

Previous Indexing

  • Lipoxygenases (1974-1986)
  • Oxygenases (1966-1973)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Arachidonate Lipoxygenases. Medical Subject Headings (MeSH). 2026. Unique ID D001091. http://id.nlm.nih.gov/mesh/2026/D001091
  2. Arachidonate Lipoxygenases. In: Wikidata. https://www.wikidata.org/wiki/Q75837450