Chemicals and Drugs

Arachidonate 15-Lipoxygenase

An enzyme that catalyzes the oxidation of arachidonic acid to yield 15-hydroperoxyarachidonate (15-HPETE) which is rapidly converted to 15-hydroxy-5,8,11,13-eicosatetraenoate (15-HETE). The 15-hydroperoxides are preferentially formed in NEUTROPHILS and LYMPHOCYTES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that catalyzes the oxidation of arachidonic acid to yield 15-hydroperoxyarachidonate (15-HPETE) which is rapidly converted to 15-hydroxy-5,8,11,13-eicosatetraenoate (15-HETE). The 15-hydroperoxides are preferentially formed in NEUTROPHILS and LYMPHOCYTES.

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Classification

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MeSH Record

Synonyms

7 entry terms
  • 15-Lipoxygenase
  • Arachidonic Acid 15-Lipoxygenase
  • 15 Lipoxygenase
  • 15-Lipoxygenase, Arachidonate
  • 15-Lipoxygenase, Arachidonic Acid
  • Arachidonate 15 Lipoxygenase
  • Arachidonic Acid 15 Lipoxygenase

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

91(87); was see under ARACHIDONATE LIPOXYGENASES 1987-90

MeSH Record

Previous Indexing

  • Lipoxygenases (1974-1986)
  • Oxygenases (1966-1973)

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Tree Numbers

AMA Style

References

  1. National Library of Medicine. Arachidonate 15-Lipoxygenase. Medical Subject Headings (MeSH). 2026. Unique ID D001093. http://id.nlm.nih.gov/mesh/2026/D001093
  2. Arachidonate 15-Lipoxygenase. In: Wikipedia. https://en.wikipedia.org/wiki/Arachidonate_15-lipoxygenase
  3. Arachidonate 15-Lipoxygenase. In: Wikidata. https://www.wikidata.org/wiki/Q22011069